| Elihu Root | Mexico, D.F., Cuernavaca, Puebla, Orizaba, Guadalajara, Potosi | Met with President Diaz, Foreign Minister Mariscal, and Governors of several
Mexican States. Delivered several public addresses Left Washington September
26. | September 29–October 16, 1907 |
| Edward Reilly Stettinius | Chapultepec | Attended Inter-American Conference on the Problems of War and Peace. | February 20–March 8, 1945 |
| John Foster Dulles | Mexico, D.F. | Attended the inauguration of President Lopez Mateos. | November 30–December 2, 1958 |
| Christian Archibald Herter | Mexico, D.F. | Attended ceremonies for the 150th anniversary of Mexican independence. | September 15–16, 1960 |
| David Dean Rusk | Mexico, D.F. | Accompanied President Johnson on an informal visit. Dedicated a statue of President
Lincoln. | April 15–16, 1966 |
| David Dean Rusk | Mexico, D.F. | Attended the inauguration of a new Foreign Office building. | September 30–October 1, 1966 |
| David Dean Rusk | Ciudad Acuna | Accompanied President Johnson on a visit to the Amistad Dam. | December 3, 1966 |
| William Pierce Rogers | Ciudad Acuna | Accompanied President Nixon to the dedication of the Amistad Dam. | September 8, 1969 |
| William Pierce Rogers | Puerto Vallarta | Accompanied President Nixon during an official visit. | August 20–21, 1970 |
| William Pierce Rogers | Mexico, D.F. | Attended the inauguration of President Echeverria. | November 29–December 1, 1970 |
| William Pierce Rogers | Cozumel | Vacation. | April 16–18, 1971 |
| William Pierce Rogers | Mexico, D.F. | Met with President Echeverria and senior Mexican officials. | May 12–14, 1973 |
| Henry A. (Heinz Alfred) Kissinger | Mexico, D.F. | Attended the Tlatelolco Conference of Latin American Foreign Ministers. | February 20–24, 1974 |
| Henry A. (Heinz Alfred) Kissinger | Acapulco, Mexico, D.F. | Honeymoon. Also met with senior Mexican officials. | March 30–April 9, 1974 |
| Henry A. (Heinz Alfred) Kissinger | Nogales, Magdalena de Kino | Accompanied President Ford to a meeting with President Echeverria. | October 21, 1974 |
| Henry A. (Heinz Alfred) Kissinger | Mexico, D.F. | Met with President Echeverria and senior Mexican officials. | June 10–13, 1976 |
| Henry A. (Heinz Alfred) Kissinger | Mexico, D.F. | Attended the inauguration of President Lopez Portillo. | November 29–December 2, 1976 |
| Cyrus Roberts Vance | Mexico, D.F., Puerto Vallarta | Official visit. Met with President Lopez Portillo and Foreign Relations Secretary
Roel. | May 3–5, 1978 |
| Cyrus Roberts Vance | Mexico, D.F. | Accompanied President Carter on a State visit. | February 14–16, 1979 |
| Edmund Sixtus Muskie | Mexico, D.F. | Official visit. Reviewed work of U.S.-Mexico Consultative Mechanism. | November 29–December 1, 1980 |
| Alexander Meigs Haig | Cancun | Attended a Foreign Ministers meeting preliminary to Conference on Cooperation and
Development. | July 31–August 2, 1981 |
| Alexander Meigs Haig | Cancun | Accompanied President Reagan to the International Meeting on Cooperation and
Development. | October 21–24, 1981 |
| Alexander Meigs Haig | Mexico, D.F. | Deposited the instrument of ratification of the Treaty for the Prohibition of
Nuclear Weapons in Latin America. | November 23–24, 1981 |
| George Pratt Shultz | Tijuana | Accompanied President Reagan to a meeting with President-elect De la
Madrid. | October 9, 1982 |
| George Pratt Shultz | Mexico, D.F. | Attended the 3rd meeting of U.S.-Mexico Binational Commission. | April 18–19, 1983 |
| George Pratt Shultz | La Paz (Baja California) | Accompanied President Reagan to a meeting with President de la Madrid. | August 14, 1983 |
| George Pratt Shultz | Mexico, D.F. | Met with President De la Madrid and senior Mexican officials. | October 11–12, 1984 |
| George Pratt Shultz | Mexico, D.F. | Attended a meeting of U.S.-Mexico Binational Commission. | July 25–26, 1985 |
| George Pratt Shultz | Mexicali | Accompanied President Reagan to a meeting with President de la Madrid. | January 3, 1986 |
| George Pratt Shultz | Mazatlan | Accompanied President Reagan to a meeting with President de la Madrid. | February 13, 1988 |
| George Pratt Shultz | Mexico, D.F. | Attended the inauguration of President Salinas de Gortari. | December 1, 1988 |
| James Addison Baker | Mexico, D.F. | Attended the 7th meeting of the U.S.-Mexico Binati. | August 6–7, 1989 |
| James Addison Baker | Mexico, D.F. | Attended meeting of the U.S.-Mexico Binational Commission. | September 8–9, 1991 |
| James Addison Baker | Mexico, D.F. | Attended the signing of the Salvadoran Peace Treaty. | January 16, 1992 |
| Warren Minor Christopher | Mexico City | Attended meeting of the U.S.-Mexico Binational Commission. | May 8–9, 1994 |
| Warren Minor Christopher | Mexico, D.F. | Attended meeting of the U.S.-Mexico Binational Commission. | May 6–7, 1996 |
| Madeleine Korbel Albright | Mexico, D.F. | Accompanied President Clinton on a State Visit and attended a meeting of the
U.S.-Mexico Binational Commission. | May 5–7, 1997 |
| Madeleine Korbel Albright | Merida | Accompanied President Clinton during a State Visit. | February 15, 1999 |
| Madeleine Korbel Albright | Oaxaca | Met with Foreign Minister Green. | January 15–16, 2000 |
| Madeleine Korbel Albright | Mexico, D.F. | Led the U.S. delegation to the inauguration of President Fox. | November 30–December 2, 2000 |
| Colin Luther Powell | San Cristobal | Accompanied President Bush to a meeting with President Fox. | February 16, 2001 |
| Colin Luther Powell | Monterrey | Accompanied President Bush to the UN Conference on International
Development. | March 21–22, 2002 |
| Colin Luther Powell | Los Cabos | Attended APEC Ministerial and Summit Meetings. | October 23–26, 2002 |
| Colin Luther Powell | Mexico, D.F. | Attended a meeting of the U.S.-Mexico Binational Commission. | November 25–26, 2002 |
| Colin Luther Powell | Monterrey | Accompanied President Bush to the Special Summit of the Americas. | January 12–13, 2004 |
| Colin Luther Powell | Mexico City | Attended U.S.-Mexico Binational Commission meeting. | November 8–9, 2004 |
| Condoleezza Rice | Mexico City | Met with senior Mexican officials. | March 10, 2005 |
| Condoleezza Rice | Merida | Accompanied President Bush. | March 12–13, 2007 |
| Condoleezza Rice | Puerto Vallarta | Met with Foreign Secretary Espinosa. | October 22–23, 2008 |
| Hillary Rodham Clinton | Mexico City, Monterrey | Met with Foreign Secretary Espinosa and discussed the Merida Initiative. | March 25–26, 2009 |
| Hillary Rodham Clinton | Mexico City | Attended a U.S.-Mexico High Level Consultative Group meeting and met with President
Calderon and Foreign Secretary Espinosa. | March 23, 2010 |
| Hillary Rodham Clinton | Guanajuato | Met with Foreign Secretary Espinosa. | January 24, 2011 |
| Hillary Rodham Clinton | Los Cabos | Attended a G-20 Ministerial Meeting. Signed U.S.-Mexico Transboundary
Agreement. | February 19–20, 2012 |
| Hillary Rodham Clinton | Los Cabos | Attended the G-20 Meeting. | June 18–19, 2012 |
| John Forbes Kerry | Mexico City | Met with President Enrico Pena Nieto and Foreign Secretary Jose Antonio Meade.
Attended a Joint Bilateral Forum on Higher Education, Innovation, and Research; a
CleanTech Challenge Launch event, and a U.S.-Mexico CEO Dialogue dinner. | May 21–22, 2014 |
| Rex W. Tillerson | Mexico City | Discussed bilateral relations with President Enrique Pena Nieto and Foreign
Minister Luis Videgaray. Was joined by Secretary of Homeland Security John
Kelly. | February 22–23, 2017 |
| Rex W. Tillerson | Mexico City | Met with President Enrique Peña Nieto and Foreign Secretary Luis
Videgaray. | February 1–2, 2018 |
| Michael R. Pompeo | Mexico City | Met with President Enrique Peña Nieto, Foreign Secretary Luis Videgaray Caso, and
President-elect Andres Manuel Lopez Obrador. | July 13, 2018 |
| Michael R. Pompeo | Mexico City | Met with President Enrique Peña Nieto, Foreign Secretary Luis Videgaray Caso, and
Foreign Secretary-designate Marcelo Luis Ebrard Casaubon. | October 19, 2018 |
| Michael R. Pompeo | Mexico City | Met with Foreign Secretary Marcelo Ebrard. | July 21, 2019 |
| Antony Blinken | Mexico City | Co-led the U.S. delegation to the U.S.-Mexico High Level Security
Dialogue. | October 7–8, 2021 |
| Antony Blinken | Mexico City | Met with Foreign Secretary Marcelo Ebrard. Co-chaired the U.S.-Mexico High-Level
Economic Dialogue (HLED). | September 12, 2022 |
| Antony Blinken | Mexico City | Attended the 10th North American Leaders’ Summit as part of President Biden's
delegation. | January 8–10, 2023 |
| Antony Blinken | Mexico City | Co-chaired the 2023 U.S.-Mexico High-Level Security Dialogue. | October 4–5, 2023 |
| Antony Blinken | Mexico City | Met with President Andrés Manuel López Obrador. | December 27, 2023 |
