| William Pierce Rogers | Nairobi | Met with President Kenyatta and senior Kenyan officials. | February 13–15, 1970 |
| Henry A. (Heinz Alfred) Kissinger | Nairobi | Met with President Kenyatta and Foreign Affairs Minister Waiyaki. | April 24–25, 1976 |
| Henry A. (Heinz Alfred) Kissinger | Nairobi | Attended an UNCTAD Conference. | May 3–6, 1976 |
| Henry A. (Heinz Alfred) Kissinger | Nairobi | Discussed Rhodesia and Namibia with President Kenyatta and Acting Foreign Minister
Osogo. | September 22–23, 1976 |
| George Pratt Shultz | Nairobi | Met with President Moi. | January 9–12, 1987 |
| Madeleine Korbel Albright | Nairobi | Visited site of the U.S. Embassy and met with President Moi. | August 18, 1998 |
| Madeleine Korbel Albright | Nairobi | Met with President Moi and inaugurated a new Embassy building. Also met with IGAD
representatives and representatives of Sudanese civil society. | October 20–23, 1999 |
| Colin Luther Powell | Nairobi | Met with President Moi, Kenyan civil and political leaders, and UN and NGO
representatives. | May 25–27, 2001 |
| Colin Luther Powell | Nairobi, Naivasha | Attended Sudanese peace talks and met with President Kibaki. | October 21–22, 2003 |
| Colin Luther Powell | Nairobi | Attended the signing of the Sudan Comprehensive Peace Agreement. | January 7–9, 2005 |
| Condoleezza Rice | Nairobi | Met with President Kibaki, former Secretary-General Annan, and Kenyan political
leaders. | February 18, 2008 |
| Hillary Rodham Clinton | Nairobi | Attended the 8th AGOA Forum. Met with Somalian President Sheikh Ahmed. | August 4–7, 2009 |
| Hillary Rodham Clinton | Nairobi | Met with President Mwai Kibaki, Chief Justice Willy Mutunga, Prime Minister Raila
Odinga, Somali Roadmap Signatories and the Independent Electoral and Boundaries
Commission and Civil Society. | August 4–5, 2012 |
| John Forbes Kerry | Nairobi | Met with President Uhuru Kenyatta and Chief Justice Willy Mutunga. Visited the
Dadaab refugee camp. | May 3–5, 2015 |
| John Forbes Kerry | Nairobi | Met with President Uhuru Kenyatta and Foreign Minister Amina Mohamed and regional
Foreign Ministers. | August 22, 2016 |
| Rex W. Tillerson | Nairobi | Met with Kenyan President Uhuru Kenyatta and Foreign Minister Monica
Juma. | March 9–11, 2018 |
| Antony Blinken | Nairobi | Met with Kenyan President Uhuru Kenyatta and Cabinet Secretary for Foreign Affairs
Ambassador Raychelle Omamo. | November 17–18, 2021 |
