| William Pierce Rogers | Kabul | Met with King Mohammad Zahir Shah and Prime Minister Etemadi. | May 25, 1969 |
| Henry A. (Heinz Alfred) Kissinger | Kabul | Official visit. Met with Prime Minister Daoud and senior Afghan
officials. | November 1, 1974 |
| Henry A. (Heinz Alfred) Kissinger | Kabul | Official visit. Met with Prime Minister Daoud and senior Afghan
officials. | August 8, 1976 |
| Colin Luther Powell | Kabul | Met with leaders of the Afghan Interim Authority. Announced the upgrading of the
U.S. Liaison Office to Embassy status. | January 17, 2002 |
| Colin Luther Powell | Kabul | Met with President Karzai and with U.S. military and civilian officials. | March 17, 2004 |
| Condoleezza Rice | Kabul | Met with President Karzai and Afghan political leaders; addressed U.S. military
personnel. | March 17, 2005 |
| Condoleezza Rice | Kabul | Met with President Karzai. | October 12, 2005 |
| Condoleezza Rice | Bagram, Kabul | Accompanied President Bush. | March 1, 2006 |
| Condoleezza Rice | Kabul | Met with President Karzai. | June 28, 2006 |
| Condoleezza Rice | Kandahar, Kabul | Accompanied British Foreign Secretary Miliband. Met with President
Karzai. | February 7, 2008 |
| Hillary Rodham Clinton | Kabul | Attended the inauguration of President Karzai. | November 18–19, 2009 |
| Hillary Rodham Clinton | Kabul | Met with President Karzai and attended an international conference on the future of
Afghanistan. | July 19–20, 2010 |
| Hillary Rodham Clinton | Kabul | Met with President Karzai and Afghan civil leaders. | October 20, 2011 |
| Hillary Rodham Clinton | Kabul | Met with President Hamid Karzai. Announced the designation of Afghanistan as a
Major Non-NATO Ally. | July 7, 2012 |
| John Forbes Kerry | Kabul | Met with President Hamid Karzai. | March 25–26, 2013 |
| John Forbes Kerry | Kabul | Met with President Hamid Karzai. Signed Bilateral Security Agreement. | October 11–12, 2013 |
| John Forbes Kerry | Kabul | Met with President Hamid Karzai, Afghan political leaders, and the head of the UN
Assistance Mission. | July 11–12, 2014 |
| John Forbes Kerry | Kabul | Met with President Hamid Karzai and presidential candidates Abdullah Abdullah and
Ashraf Ghani. | August 7–8, 2014 |
| John Forbes Kerry | Kabul | Attended the third meeting of the U.S.-Afghanistan Bilateral Commission. | April 9, 2016 |
| Rex W. Tillerson | Bagram | Met with President Ashraf Ghani. | October 23, 2017 |
| Michael R. Pompeo | Kabul | Met with Afghan officials. | July 9, 2018 |
| Michael R. Pompeo | Kabul | Met with President Ashraf Ghani, Chief Executive Abdullah Abdullah, former
President Hamid Karzai, and others to discuss next steps in the Afghan Peace
Process. | June 25, 2019 |
| Michael R. Pompeo | Kabul | Met with Afghan President Ashraf Ghani and Afghan Security Ministers. | March 23, 2020 |
| Antony Blinken | Kabul | Met with Afghan leaders and civil society. | April 15, 2021 |
